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Are COVID vaccines designed to cause blood clots?

The Claim:

Anti-vaxxers on Twitter claim that a former pharmaceutical VP has revealed that COVID mRNA vaccines were designed to cause blood clots on purpose.

The Facts:

Of note, this former VP doubts that SARS-CoV-2, the virus that causes COVID, ever existed, so you have to consider the veracity of the source.

The video describes what they claim are the mechanisms of mRNA vaccines: he claims that any cell that uptakes and produces the spike protein will be recognized by our immune systems and destroyed. While some of this is accurate, it displays a fundamental misunderstanding of how and why vaccines work.

Vaccines, in general, work by introducing bits of pathogen, called antigens, to your body, so it can learn to fight the real pathogen. With mRNA vaccines, instead of supplying the antigen itself, the vaccine supplies the instructions for your body to build the antigen itself. The vaccine does not enter the bloodstream directly. So it’s less likely to interact with components of the blood that can lead to clotting.

The vaccine is administered in the deltoid muscle. The vast majority of the vaccine is taken up by the cells of the muscle and by dendritic cells, immune cells that present foreign antigens to the immune system. This immune response is highly specific to the spike protein and does not affect the blood’s coagulation system or clotting factors.

The vaccine contains a finite amount of mRNA, and only a finite number of cells interact with the vaccine. The vaccine is designed to stimulate the immune system in a controlled way, and the disease replicates uncontrolled and infects almost every cell of your body.

With over 600 million doses of mRNA vaccine given in the US, there has been no indication of an increased risk of blood clots.

Disclaimer: Science is always evolving and our understanding of these topics may have evolved too since this was originally posted. Be sure to check out our most recent posts and browse the latest Just the Facts Topics for the latest.

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